AMLODAC CH Tablet is used in the treatment of hypertension (high blood pressure)

AMLODAC CH Tablet may also be prescribed for other conditions as determined by your doctor.

• Amlodipine Besylate belongs to a group of medicines known as calcium channel blockers. Amlodipine Besylate prevents the calcium from moving into the blood vessel wall thereby preventing tightening of blood vessel walls. This reduces the blood pressure and improves symptoms of chest pain.

• Chlorthalidone belongs to group of medicines called thiazide-like diuretics. Diuretics are medications which cause increase water removal from body as urine. Chlorthalidone removes excess sodium, chloride and water by kidney, thereby reducing the blood pressure. Chlorthalidone has a long term and more effective action on reduction of blood pressure than other thiazide and thiazide-like diuretics.

AMLODAC CH Tablet act additively to reduce the blood pressure.

• The dosage of oral tablets of AMLODAC CH Tablet depends on the age, weight and medical condition of an individual. Take AMLODAC CH Tablet as prescribed by your doctor.
• You must swallow the tablet with a glass of water. Do not chew the tablet.
• Take your daily dose at same time (preferably at breakfast).
• Do not take the tablet with grapefruit juice (it can lead to increase in amlodipine concentration which would increase the lowering of the blood pressure).
• AMLODAC CH Tablet is not recommended for children and adolescent under 18 years of age.
• Do not discontinue the medication without consulting a doctor.
• If you miss a dose of AMLODAC CH Tablet, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

If you have taken an overdose of AMLODAC CH Tablet, please contact your doctor immediately.

Symptoms of overdose of Amlodipine Besylate may include the following:

• Dizziness
• Light headedness
• Fainting, weakness
• Cool and clammy skin
• Hypotension (low blood pressure)
• Loss of consciousness

Symptoms of overdose of Chlorthalidone may include the following:

• Dehydration
• Diarrhoea or constipation, abdominal pain
• Dizziness, fainting
• Electrolyte imbalance (hypokalaemia (low levels of potassium in blood), hypochloraemia (low levels of chloride ions in blood), hyponatremia (low levels of sodium in the blood)
• Lethargy
• Nausea
• Weakness

Drugs that interact with Amlodipine Besylate:

• Cyclosporin, Tacrolimus
• Dantrolene
• Diltiazem, Verapamil
• Ketoconazole, Itraconazole
• Rifampicin, Erythromycin, Clarithromycin
• Ritonavir, Indinavir, Nelfinavir
• Simvastatin
• St Johns wort

Drugs that interact with Chlorthalidone:

• Adrenaline
• Alcohol
• Amantadine
• Aminoglycoside antibiotics
• Atropine, Biperiden
• Barbiturates
• Cholestyramine, Colespitol
• Corticosteroids
• Cytotoxic drugs
• Insulin, Oral anti-diabetic drugs
• Lithium
• Narcotic drugs
• NSAIDs (non-steroidal anti-inflammatory drugs)
• Tubocurarine

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

Most common side effects of AMLODAC CH Tablet are:

• Weakness, pain, fatigue, malaise
• Headache, dizziness, vertigo, nervousness, depression
• Increased muscle tone, decreased sensations
• Anxiety
• Low blood pressure, fainting, palpitation, irregular rhythm, increased heart rate, chest pain, heart attack
• Dry mouth, thirst, loss of appetite, nausea, vomiting, abdominal pain, diarrhoea or constipation, passing of gas, weight changes
• Increased sweating, skin discolouration
• Muscle cramps, back pain, pain in joints
• Abnormal vision

Please contact your physician immediately if you have

• allergic reactions (swelling of the face, mouth, larynx (voice box), itching and rash);
• severe light-headedness or fainting;
• angioneurotic oedema (red, burning, itching areas on skin near eyes, lips, hands, feet and inside of throat, hoarseness of voice, difficulty in breathing);
• low levels of serum potassium;
• severe skin allergies such as blisters on skin, mouth, lips, eyes and genitals (commonly called Steven Johnsons syndrome).

This is not a comprehensive list of side effects. Consult your doctor to know more about other possible side effects.

Seek doctors advice before taking any other drug or herbal products while on AMLODAC CH Tablet.

You are advised not to take AMLODAC CH Tablet if

• it has passed the expiry date of the medicine printed on the pack.
• the foil or packaging is torn or shows signs of tampering or there is discoloration.

Tell your doctor if

• you are allergic to AMLODAC CH Tablet or to any ingredients of this medicine.
• you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
• you have low levels of potassium in blood.
• you have had hypersensitivity reaction to Chlorthalidone before.
• you have diabetes.
• You have had angioedema.
• you are under dialysis.
• you have renal artery stenosis (narrowed blood vessel in kidney) or have had a kidney transplant.
• you have liver disease.
• you have systemic lupus erythematosus (SLE) (an autoimmune disease).
• you are planning a surgery or any procedure.
• you are pregnant or trying to conceive or are breastfeeding.

If you have taken an overdose of AMLODAC CH Tablet, please contact your doctor immediately.

Symptoms of overdose of Amlodipine Besylate may include the following:

• Dizziness
• Light headedness
• Fainting, weakness
• Cool and clammy skin
• Hypotension (low blood pressure)
• Loss of consciousness

Symptoms of overdose of Chlorthalidone may include the following:

• Dehydration
• Diarrhoea or constipation, abdominal pain
• Dizziness, fainting
• Electrolyte imbalance (hypokalaemia (low levels of potassium in blood), hypochloraemia (low levels of chloride ions in blood), hyponatremia (low levels of sodium in the blood)
• Lethargy
• Nausea
• Weakness

1. How should AMLODAC CH Tablet be stored?

AMLODAC CH Tablet should be stored below 30C. Keep the medicine away from sunlight and do not freeze the medicine. Keep the medicine out of reach from children.

2. Can I drive while taking AMLODAC CH Tablet?

AMLODAC CH Tablet causes drowsiness, dizziness and headache in some individuals. Avoid driving if you are taking AMLODAC CH Tablet.

3. Should I follow any special dietary instructions while taking AMLODAC CH Tablet + Telmisartan?

Do not take grapefruit or grapefruit juice while on AMLODAC CH Tablet. Apart from this, there are no dietary restrictions if you are taking AMLODAC CH Tablet.

4. Can I drink alcohol while taking AMLODAC CH Tablet?

No, it is not advisable to consume alcohol while on AMLODAC CH Tablet as it can make you dizzy, sleepy or tired.

5. Is AMLODAC CH Tablet addictive?

No, AMLODAC CH Tablet is not addictive. However, do not take it without consulting your doctor.