What BRINZOTIM is used for?

• It is used to treat high pressure in the eyes also called glaucoma or ocular hypertension in adult patients that are more than 18 years of age and in whom high pressure in the eyes cannot be controlled effectively by one medicine alone

Tell your doctor if you are taking medicines such as:

• medicines to lower blood pressure like para sympathomimetics and guanetidine
• quinidine used to treat heart conditions and some types of malaria
• amiodarone or other medicines to treat heart rhythm disorders and glycosides to treat heart failure
• medicines to treat diabetes, gastric ulcers
• antifungal, antiviral or antibiotic
• antidepressants such as fluoxetine and paroxetine
• carbonic anhydrase inhibitor (acetazolamide or dorzolamide)
• adrenaline (epinephrine)
• diuretics (water tablets)

• Always use this medicine exactly as your doctor has told you
• If you are changing from another eye drop medicine used to treat glaucoma to BRINZOTIM , you should stop using the other medicine and start using BRINZOTIM the following day
• The recommended dose is one drop in the affected eye or eyes, twice a day
• Only use BRINZOTIM in both eyes if your doctor told you to do so

How to use:

• Wash your hands
• Shake well before use
• Twist off the bottle cap. After the cap is removed, if the tamper evident snap collar is loose, remove before using product
• Tilt your head back. Pull down your eyelid with a clean finger, until there is a pocket between the eyelid and your eye. The drop will go in here
• Bring the bottle tip close to the eye. Use the mirror if it helps
• Do not touch your eye or eyelid, surrounding areas or other surfaces with the dropper. It could infect the drops
• Gently press on the base of the bottle to release one drop of BRINZOTIM at a time
• Do not squeeze the bottle it is designed so that a gentle press on the bottom is all that it needs
• After using BRINZOTIM , press a finger into the corner of your eye, by the nose for 2 minutes. This helps to stop the medicine getting into the rest of the body
• If you use drops in both eyes, repeat the steps for your other eye
• Close the bottle cap firmly immediately after use
• If a drop misses your eye, try again
• If you are using other eye drop or eye ointment medicines leave at least 5 minutes between each medicine and eye ointments should be administered last

If you use more BRINZOTIM

• If you have taken more BRINZOTIM rinse your eye with warm water. Do not put in any more drops until it is time for your next regular dose
• You may experience a decreased heart rate, decreased blood pressure, heart failure, difficulty in breathing, and your nervous system may be affected

If you forget to use BRINZOTIM

• Do not take a double dose to make up for forgotten individual doses. If you have forgotten to take your medicine, take it as soon as you remember

If you stop using BRINZOTIM

• Do not stop taking the BRINZOTIM without speaking to your doctor, the pressure in your eye will not be controlled which could lead to loss of sight