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What is DIGENE TOTAL?
- DIGENE TOTAL is a selective “proton pump inhibitor” which contains the active substance pantoprazole
CONSUMER MEDICINE INFORMATION
THERAPEUTIC USES
WARNING & PRECAUTIONS
INTERACTIONS
DIRECTIONS FOR USE
SIDE EFFECTS
MORE INFORMATION
What DIGENE TOTAL is used for?
It is used,
- For reducing the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine
- In reflux oesophagitis. An inflammation of your oesophagus caused by stomach acids
- To treat infection with a bacterium called Helicobacter pylori in patients with duodenal and stomach ulcers in combination with two antibiotics
- In stomach and duodenal ulcers
- To treat Zollinger-Ellison-Syndrome
Talk to your doctor, before taking DIGENE TOTAL, if you:
- are allergic to pantoprazole or to any of the other ingredients of this medicine.
- are allergic to medicines containing other proton pump inhibitors
- your Vitamin B12 deficient
- have ever had a skin reaction after treatment with a medicine like Pantoprazole that reduces stomach acid
- get a rash on your skin, especially in areas exposed to the sun tell your doctor as soon as you can, as you may need to stop your treatment with Pantoprazole. Remember to also mention any other ill-effects like pain in your joints
- are due to have a specific blood test (Chromogranin A)
- If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine
Tell your doctor if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription.
- Medicines used to treat fungal infections or used for certain types of cancer
- Atazanavir
- Warfarin and phenprocoumon, which affect the thickening, or thinning of the blood
- Methotrexate (used to treat rheumatoid arthritis, psoriasis, and cancer)
- Fluvoxamine (used to treat depression and other psychiatric diseases)
- Rifampicin (used to treat infections)
- St John’s wort (Hypericum perforatum) (used to treat mild depression)
- Always take this medicine exactly as how you are told to take.
- Take the tablets 1 hour before a meal without chewing or breaking them and swallow them whole with some water
Patients with kidney problems
- If you have kidney problems, you should not take Pantoprazole for eradication of Helicobacter pylori
Patients with liver problems
- If you suffer from severe liver problems, you should not take more than one tablet 20 mg pantoprazole a day. In the case of a rise of liver enzymes the treatment should be stopped. You should not take Pantoprazole for eradication of Helicobacter pylori if u have liver problem
If you take more DIGENE TOTAL
- If you take more DIGENE TOTAL, consult your doctor. There are no known symptoms of overdose
If you forget to take DIGENE TOTAL
- Do not take a double dose to make up for a forgotten dose. Take your next, normal dose at the usual time
If you stop taking DIGENE TOTAL
- Do not stop taking these tablets without first talking to your doctor
Like all medicines, this medicine can cause side effects, although not everybody gets them.
SERIOUS
COMMON
UNCOMMON
RARE
VERY RARE
- allergic reactions marked by swelling of the tongue and/or throat, difficulty in swallowing, hives (nettle rash), difficulties in breathing, allergic facial swelling, severe dizziness with very fast heartbeat and heavy sweating
- skin conditions marked by blistering of the skin and rapid deterioration of your general condition, erosion (including slight bleeding) of eyes, nose, mouth/lips or genitals, and sensitivity to light
- yellowing of the skin or whites of the eyes (severe damage to liver cells, jaundice) or fever, rash, and enlarged kidneys sometimes with painful urination, and lower back pain (serious inflammation of the kidneys), possibly leading to kidney failure
- headache, dizziness
- diarrhea, feeling sick, vomiting, vomiting blood, bloating and flatulence (wind)
- constipation
- dry mouth, exanthema, eruption
- itching, feeling weak, exhausted or generally unwell
- sleep disorders
- fracture in the hip, wrist or spine, increase in liver enzymes
- distortion or complete lack of the sense of taste
- blurred vision
- weight changes
- swelling of the extremities (peripheral oedema)
- depression
- breast enlargement in males, increase in bilirubin
- increased fat levels in blood
- sharp drop in circulating granular white blood cells
- disorientation, reduction in the number of blood platelets, which may cause you to bleed or bruise more than normal
- a reduction in the number of white blood cells, which may lead to more frequent infections
- coexisting abnormal reduction in the number of red and white blood cells, as well as platelets
