WHAT IS IBYZOLE D 40/30MG?

IBYZOLE D 40/30MG contains domperidone and pantoprazole

Domperidone belongs to a group of medicines called dopamine antagonists

Pantoprazole is a selective “proton pump inhibitor”, a medicine which reduces the amount of acid produced in your stomach

What IBYZOLE D 40/30MG is used for?

It is used:

• for Reflux oesophagitis, an inflammation of your oesophagus accompanied by the regurgitation of stomach acid
• to treat infection with a bacterium called Helicobacter pylori in patients with duodenal ulcers and stomach ulcers in combination with two antibiotics (eradication therapy)
• to treat Zollinger-Ellison-Syndrome and other conditions producing too much acid in the stomach
• to treat nausea and vomiting

TALK TO YOUR DOCTOR

Talk to your doctor before taking this medicine, if you:

• are allergic (hypersensitive) to domperidone, pantoprazole or any of the other ingredients of this medicine
• are allergic to medicines containing other proton pump inhibitors
• have black, tarry bowel motions (stools) or notice blood in your bowel motions.
• have a blockage or tear in your intestines
• have a tumor of the pituitary gland called a prolactinoma
• have a moderate or severe liver and kidney disease
• have a heart problem called prolonged QT corrected interval
• have or had heart failure
• have a problem that gives you a low level of potassium or magnesium, or a high level of potassium in your blood
• are due to have a specific blood test (Chromogranin A)
• suffer from unintentional loss of weight

• Talk to your doctor if you are taking medicines such as,
• oral ketoconazole, fluconazole or voriconazole used for fungal infections
• erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine used for bacterial infections
• heart problems or high blood pressure (e.g., amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil)
• haloperidol, pimozide, sertindole used for psychoses
• citalopram, escitalopram used for depression
• gastro-intestinal disorders (e.g., cisapride, dolasetron, prucalopride)
• mequitazine, mizolastine used for allergy
• halofantrine used for malaria
• protease inhibitors used for AIDS/HIV
• toremifene, vandetanib, vincamine, erlotinib used for cancer
• apomorphine
• warfarin and phenprocoumon, which affect the thickening, or thinning of the blood
• methotrexate (used to treat rheumatoid arthritis, psoriasis, and cancer)
• fluvoxamine (used to treat depression and other psychiatric diseases)
• rifampicin (used to treat infections)
• St John’s wort (Hypericum perforatum) (used to treat mild depression)

Always take this medicine exactly as your doctor has told you For oral use only It must be swallowed with a glass of water Take this medicine 30 minutes before meals

Q. If you take more IBYZOLE D 40/30MG

If you or someone else have used or taken too much IBYZOLE D 40/30MG, contact your doctor or nearest hospital casualty department immediately

Q. If you forget to take IBYZOLE D 40/30MG

If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose

Q. If you stop taking IBYZOLE D 40/30MG

Do not stop taking IBYZOLE D 40/30MG without first talking to your doctor

Like all medicines, the medicine can have side effects, although not everybody gets them.

SERIOUS

Domperidone:

• swelling of the hands, feet, ankles, face, lips or throat
• difficulty in swallowing or breathing
• uncontrolled movements - irregular eye movements, unusual movements of the tongue, and abnormal posture such as a twisted neck, trembling and muscle stiffness
• very fast or unusual heartbeat

Pantoprazole:

swelling of the hands, feet, ankles, face, lips or throat which may cause difficulty in swallowing or breathing

COMMON

Domperidone:

dry mouth

Pantoprazole:

benign polyps in the stomach

UNCOMMON

Domperidone:

• anxiety
• loss of interest in sex
• sleepiness or headache, diarrhoea
• rash or itchiness
• painful or tender breasts, or discharge from breasts
• a general feeling of weakness

Pantoprazole:

• headache, dizziness
• feeling sick, vomiting bloating and flatulence (wind)
• constipation
• abdominal pain and discomfort
• skin rash, exanthema, eruption
• itching, feeling weak, exhausted or generally unwell
• sleep disorders
• fracture in the hip, wrist or spine
• increase in liver enzymes

RARE

Pantoprazole:

• distortion or complete lack of the sense of taste
• disturbances in vision such as blurred vision
• hives, weight changes
• pain in the joints or muscle
• raised body temperature- sharp drop in circulating granular white blood cells
• swelling of the extremities (peripheral oedema)
• allergic reactions, depression
• breast enlargement in males
• increase in bilirubin, increased fat levels in blood

VERY RARE

Pantoprazole:

• disorientation
• reduction in the number of blood platelets

STORAGE

• Keep out of reach of children
• Store at room temperature (15-25ºC)
• Do not use this medicine after the expiry date

Disclaimer:

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.