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What is NOKLOT CV 75MG?
- NOKLOT CV 75MG contains an active ingredient called Aspirin, Atorvastatin and Clopidogrel
Aspirin
- Aspirin belongs to a group of medicines called antiplatelet agents that help prevent your blood cells sticking together and forming a blood clot
Atorvastatin
- Atorvastatin belongs to a group of medicines known as statins, which are lipid (fat) regulating medicines
Clopidogrel
- Clopidogrel belongs to a group of medicines called antiplatelet medicinal products
CONSUMER MEDICINE INFORMATION
THERAPEUTIC USES
WARNING & PRECAUTIONS
INTERACTIONS
DIRECTIONS FOR USE
SIDE EFFECTS
MORE INFORMATION
What NOKLOT CV 75MG is used for?
It is used
- to prevent blood clots forming following a heart attack or stroke or to help prevent heart attacks and strokes in patients who have previously suffered from these conditions
- to lower lipids known as cholesterol and triglycerides in the blood when a low-fat diet and life style changes on their own have failed
Talk to your doctor before taking this medicine, if you,
- are allergic to NOKLOT CV 75MG or any of the ingredients
- are allergic to other salicylates or nonsteroidal anti-inflammatory drugs
- have had an asthma attack or swelling of some parts of the body e.g. face, lips, throat or tongue (angioedema) after taking salicylates or NSAIDs
- have or have ever had an ulcer in your stomach
- have ever had the problem of your blood not clotting properly
- are suffering from gout
- have severe liver or kidney problems
- have high blood pressure
- have any severe respiratory failure
- have heavy menstrual periods
- have a planned or recent surgery (including dental) in the next seven days
- have an under-active thyroid gland (hypothyroidism)
- have had previous muscular problems during treatment with other lipid-lowering medicines (e.g. other ‘-statin’ or ‘-fibrate’ medicines)
NOKLOT CV 75MG with food, drink and alcohol
- Do not take more than one or two small glasses of grapefruit juice per day because large quantities of grapefruit juice can change the effects of NOKLOT CV 75MG
- Avoid drinking too much alcohol while taking this medicine. Drinking alcohol may possibly increase the risk of gastrointestinal bleeding and prolong bleeding time
- If you are pregnant or planning to become pregnant or breast feed, you should tell your doctor before taking this medicine. You should not breast-feed while taking this medicine
Please tell your doctor if you are taking or have recently taken any other medicines, including
- blood thinning medicines (e.g. warfarin, heparin, phenindione and clopidogrel)
- organ rejection after transplantation (e.g. ciclosporin, tacrolimus)
- high blood pressure (e.g. diuretics and ACE-inhibitors)
- regulation of the heart beat (digoxin)
- manic-depressive illness (lithium)
- pain and inflammation (e.g. anti-inflammatory medicines such as ibuprofen, or steroids)
- gout (e.g. probenecid)
- epilepsy (valproate, phenytoin, carbamazepine)
- glaucoma (acetazolamide)
- cancer or rheumatoid arthritis (e.g. methotrexate, paclitaxel)
- diabetes (e.g. glibenclamide, repaglinide)
- depression (selective serotonin re-uptake inhibitors (SSRIs) such as sertraline or paroxetine, moclobemide)
- hormone replacement therapy when the adrenal glands or pituitary gland have been destroyed or removed, or to treat inflammation, including rheumatic diseases and inflammation of the intestines (corticosteroids)
- iron salts (for treatment of iron deficiency anaemia), carbonates (treatment of peptic ulcer and reflux), alkali hydroxides (antacids)
- omeprazole or esomeprazole, medicines to treat upset stomach
- fluconazole or voriconazole, medicines to treat fungal infections
- medicine to treat HIV (human immunodeficiency virus) infections
- some calcium channel blockers used for angina or high blood pressure, e.g. amlodipine, diltiazem; medicines to regulate your heart rhythm e.g. digoxin, verapamil, amiodarone
- some medicines used in the treatment of hepatitis C e.g. telaprevir
- medicine called fusidic acid, (a medicine for bacterial infection) orally or by injection. The combination of fusidic acid and Atorvastatin can lead to serious muscle problems (rhabdomyolysis)
- Your doctor will have decided the right dose of NOKLOT CV 75MG for you
- They should be taken orally with a glass of water
- It can be taken at any time of day, with or without food
If you take more NOKLOT CV 75MG
- If you accidently take more than your usual daily dose, contact your doctor or nearest hospital for advice
If you forget to take NOKLOT CV 75MG
- If you miss a dose, wait until it is time for your next dose, then go on as normal. Do not take a double dose to make up for a forgotten dose
If you stop taking NOKLOT CV 75MG
- Do not stop the treatment unless your doctor tells you so
Like all medicines, NOKLOT CV 75MG can cause side effects, although not everybody gets them.
SERIOUS
COMMON
UNCOMMON
RARE
VERY RARE
Aspirin:
- sudden wheezing
- swelling of your lips, face or body
- rash, fainting or difficulties swallowing
- reddening of the skin with blisters or peeling and may be associated with a high fever and joint pains
- unusual bleeding, such as coughing up blood, blood in your vomit or urine, or black stools
Atorvastatin:
- muscle weakness, tenderness or pain
Clopidogrel:
- signs of liver problems such as yellowing of the skin and/or the eyes (jaundice)
- fever, signs of infection or extreme tiredness
Aspirin:
- indigestion
- increased tendency for bleeding
Atorvastatin:
- inflammation of the nasal passages, pain in the throat, nose bleed
- allergic reactions
- increases in blood sugar levels
- headache
- joint pain, muscle pain and back pain
- blood test results that show your liver function can become abnormal
Clopidogrel:
- bleeding may occur as bleeding in the stomach or bowels, bruising, haematoma (unusual bleeding or bruising under the skin), nose bleed, blood in the urine
- in a small number of cases, bleeding in the eye, inside the head, the lung or the joints
Aspirin:
- hives
- breathing difficulty
Atorvastatin:
- anorexia (loss of appetite)
- weight gain, decreases in blood sugar levels
- having nightmares, insomnia
- dizziness, numbness or tingling in the fingers and toes
- blurred vision
- ringing in the ears and/or head
- pancreatitis (inflammation of the pancreas leading to stomach pain)
- hepatitis (liver inflammation)
- rash, skin rash and itching, hives, hair loss
- neck pain, muscle fatigue
- fatigue, feeling unwell, weakness
Clopidogrel:
- headache
- rashes, itching, dizziness, sensation of tingling and numbness
Aspirin:
- severe bleeding in the stomach or intestines, brain haemorrhage; altered number of blood cells
- nausea and vomiting
- cramps in the lower respiratory tract
- asthma attack
- inflammation in the blood vessels
- bruising with purple spots (cutaneous bleeding)
- abnormal heavy or prolonged menstrual periods
Atorvastatin:
- visual disturbance
- unexpected bleeding or bruising
- cholestasis (yellowing of the skin and whites of the eyes)
- tendon injury
Clopidogrel:
- vertigo, enlarged breasts in males
Atorvastatin:
- an allergic reaction - symptoms may include s
