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What is PAXGEM XR 12.5MG?
- PAXGEM XR 12.5MG contains Paroxetine which belongs to a group of medicines called selective serotonin reuptake inhibitor
- People who are depressed or anxious have lower levels of serotonin than others. SSRIs help by increasing the level of serotonin in the brain
CONSUMER MEDICINE INFORMATION
THERAPEUTIC USES
WARNING & PRECAUTIONS
INTERACTIONS
DIRECTIONS FOR USE
SIDE EFFECTS
MORE INFORMATION
What PAXGEM XR 12.5MG is used for?
PAXGEM XR 12.5MG is used to treat,
- obsessive compulsive disorder (repetitive, obsessive thoughts with uncontrollable behaviour)
- panic disorder (panic attacks, including those caused by agoraphobia, which is a fear of open spaces)
- social anxiety disorder (fear or avoidance of social situations)
- post-traumatic stress disorder (anxiety caused by a traumatic event) and generalized anxiety disorder (generally feeling very anxious or nervous)
- depression or anxiety disorders properly is important to help you get better
Talk to your doctor before taking PAXGEM XR 12.5MG, if you:
- have kidney,liver,heart problems
- are epileptic
- had episodes of mania
- are undergoing electroconvulsive therapy
- have history of bleeding disorder
- are diabetic
- suffer from glaucoma
Taking with alcohol:
- Do not drink alcohol while you are taking PAXGEM XR 12.5MG. Alcohol may make your symptoms or side effects worse
PAXGEM XR 12.5MG can also affect the way some other medicines work. These include:
- medicines called monoamine oxidase inhibitors (MAOIs, including moclobemide and methylthionium chloride (methylene blue))
- thioridazine or pimozide, which are anti-psychotics
- aspirin (acetylsalicylic acid), ibuprofen or other medicines called NSAIDs (non-steroidal anti-inflammatory drugs
- tramadol and pethidine, painkillers
- medicines called triptans, such as sumatriptan, used to treat migraine
- other antidepressants including other SSRIs, tryptophan and tricyclic antidepressants like clomipramine, nortriptyline and desipramine
- mivacurium and suxamethonium (used in anaesthesia)
- medicines such as lithium, risperidone, perphenazine, clozapine (called anti-psychotics) used to treat some psychiatric conditions
- fentanyl, used in anaesthesia or to treat chronic pain
- a combination of fosamprenavir and ritonavir, which is used to treat Human Immunodeficiency Virus (HIV) infection
- St Johns Wort, an herbal remedy for depression
- phenobarbital, phenytoin, sodium valproate or carbamazepine, used to treat fits or epilepsy
- atomoxetine which is used to treat attention deficit hyperactivity disorder (ADHD)
- procyclidine, used to relieve tremor, especially in Parkinsons disease
- warfarin or other medicines (called anticoagulants) used to thin the blood
- propafenone, flecainide and medicines used to treat an irregular heartbeat
- metoprolol, a beta-blocker used to treat high blood pressure and heart problems
- pravastatin, used to treat high cholesterol
- rifampicin, used to treat tuberculosis (TB) and leprosy
- linezolid, an antibiotic
- tamoxifen, which is used to treat breast cancer or fertility problems
- Always take this medicine exactly as your doctor has told you
- Taking PAXGEM XR 12.5MG in the morning with food will reduce the likelihood of you feeling sick (nausea)
- Swallow them with a drink of water
- Do not chew the medicine
- The maximum dose for people over 65 is 40 mg per day
- If you have trouble with your liver or kidneys, your doctor may decide that you should have a lower dose of PAXGEM XR 12.5MG than usual
If you take more PAXGEM XR 12.5MG
- If you take too many PAXGEM XR 12.5MG, tell your doctor or a hospital straight away
If you forget to take PAXGEM XR 12.5MG
- If you do forget a dose, and you remember before you go to bed, take it straight away
- Do not take a double dose to make up for a forgotten dose
If you stop taking PAXGEM XR 12.5MG
- Do not stop taking PAXGEM XR 12.5MG until your doctor tells you to
Like all medicines, this medicine can cause side effects, although not everybody gets them.
SERIOUS
COMMON
UNCOMMON
RARE
VERY RARE
- increases in the level of cholesterol in the blood
- lack of appetite
- insomnia or feeling sleepy
- abnormal dreams
- feeling dizzy or weak or shaky (tremors)
- headache
- difficulty in concentrating feeling agitated
- blurred vision
- yawning, dry mouth
- diarrhoea or constipation
- vomiting
- weight gain
- sweating
- abnormal production of breast milk in men and women
- a slow heartbeat
- effects on the liver showing up in blood tests of your liver function
- panic attacks
- overactive behaviour or thoughts (mania)
- feeling detached from yourself (depersonalization)
- feeling anxious
- irresistible urge to move the legs (restless legs syndrome)
- pain in the joints or muscles
- increase in a hormone called prolactin in the blood
- menstrual period disorders
- skin rash, a widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome) or on much of the body surface (toxic epidermal necrolysis)
- liver problems that make the skin or whites of the eyes go yellow
- antidiuretic hormone production (SIADH)
- fluid or water retention (which may cause swelling of the arms or legs)
- sensitivity to sunlight
- painful erection of the penis
- low blood platelet count
- some patients have developed buzzing, hissing, whistling, ringing or other persistent noise in the ears (tinnitus)
- an increased risk of bone fractures
