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What is SPILACTONE T?
- SPILACTONE T which contains Spironolactone and Torsemide
- Spironolactone belong to a group of medicines called potassium-sparing diuretics (water tablets), which help you lose excess fluid from your body
- Torasemide belong to a group of drugs called diuretics or ‘water tablets’ that help to remove excess retained water from the body
CONSUMER MEDICINE INFORMATION
THERAPEUTIC USES
WARNING & PRECAUTIONS
INTERACTIONS
DIRECTIONS FOR USE
SIDE EFFECTS
MORE INFORMATION
What SPILACTONE T is used for?
Spironolactone used to treat,
- congestive heart failure
- nephrotic syndrome (a kidney disorder)
- liver cirrhosis with fluid retention (oedema) and swelling of the abdomen (ascites)
- a cancerous disease with swelling of the abdomen (malignant ascites)
Torasemide used to treat,
- high blood pressure and Oedema (fluid retention) caused by heart failure
Talk to your doctor before taking this medicine, if you:
- are allergic (hypersensitive) to Spironolactone or Torasemide or any of the other ingredients in SPILACTONE T
- have diabetes with or without kidney problems
- have Addison’s disease (weakness, loss of energy, low blood pressure and dark pigmentation of the skin)
- have high blood levels of potassium
- are not passing urine
- have low blood levels of sodium
- have liver cirrhosis
- have a severe illness
- have an inherited disorder of the red blood pigment hemoglobin causing skin blisters, abdominal pain and nervous system disorders (porphyria)
- have abnormal periods or swollen breasts
- have suffer from low blood pressure (feeling faint or dizzy)
- suffer from gout
- have hypovolemia (an abnormally low volume of blood in the circulation)
- have an abnormal heart beat
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Especially:
- blood pressure lowering medicines (antihypertensives) such as ACE inhibitors (e.g. captopril or enalapril) and angiotensin-II receptor antagonists (such as valsartan or losartan)
- chlorpropamide or insulin (used in diabetes)
- digoxin (used in some heart conditions)
- ciclosporin or tacrolimus (used to prevent organ transplant rejection, treat rheumatoid arthritis, eczema or psoriasis)
- fludrocortisone (a corticosteroid)
- warfarin (used to thin the blood)
- other potassium-sparing diuretics (water tablets)
- lithium (used for some mental illnesses)
- non-steroidal anti-inflammatory drugs (NSAIDs) such as indomethacin and mefenamic acid
- potassium supplements (potassium salts)
- noradrenaline (norepinephrine) (used for low blood pressure or heart problems)
- an anesthetic
- carbenoxolone (an ulcer healing drug)
- trimethoprim and trimethoprim-sulfamethoxazole
- corticosteroids, e.g. prednisolone
- a treatment for depression; salicylates
- used as painkillers and to reduce inflammation, e.g. aspirin
- cisplatin, which is used to treat cancer
- aminoglycoside antibiotics, e.g. gentamicin, cefalexin
- muscle-relaxing drugs, e.g. tubocurarine; or theophylline
- medicine used to prevent kidney problems, as the effect of Torasemide may be reduced sympathomimetic drugs, e.g. adrenaline, noradrenaline and ephedrine
- Always take this medicine exactly as your doctor has told you
- Swallow the tablet with water and preferably with food
If you take more SPILACTONE T
- If you (or someone else) swallow a lot of tablets at the same time, or you think a child may have swallowed any, contact your nearest hospital casualty department or tell your doctor immediately
If you forget to take SPILACTONE T
- If you forget to take a dose, take it as soon as you remember it and then take the next dose at the right time. Do not take a double dose to make up for a forgotten dose
If you stop taking SPILACTONE T
- Do not stop taking your tablet even if you are feeling well unless your doctor tells you
Like all medicines, SPILACTONE T tablets can cause side effects, although not everybody gets them.
SERIOUS
COMMON
UNCOMMON
RARE
VERY RARE
Spironolactone:
- itchiness and blistering of the skin around the lips and the rest of the body (Stevens-Johnson syndrome)
- detachment of the top layer of skin from the lower layers of skin, all over the body (toxic epidermal necrolysis)
- skin rash, fever and swelling (which could be symptoms of something more serious, drug rash and eosinophilia and systemic symptoms)
- yellow skin and eyes (jaundice)
- irregular heartbeat which can be fatal, tingling sensation, paralysis (loss of muscle function) or difficulty in breathing
Torsemide:
- allergic reaction (swelling of the lips, face or neck leading to severe difficulty in breathing; skin rash or nettle rash)
Spironolactone:
- nausea, stomach upset
- confusion, dizziness
- menstrual problems in women
- change in sex drive for both men and women (libido)
- disturbances in body electrolytes
- reduced number of cells that fight infection
- excessive growth of breast tissue in men (gynaecomastia, this goes away when treatment is stopped), breast lumps, breast pain
- skin allergy with development of itchiness and weals (urticaria), excessive hair growth (hypertrichosis), skin condition presenting with fluid-filled blisters (pemphigoid)
- hair loss
- general weakness, muscle or leg cramps
- raised potassium in the blood (hyperkalaemia)
Torsemide:
- headache
- drowsiness
- weakness and muscle cramps
- loss of appetite
- low blood pressure (feeling dizzy and faint) if you suffer from alkalosis (a change in the acid/base balance of the body) this may be worsened confusion stomach pain
Torsemide:
- inflammation of the pancreas, (nausea, vomiting, abdominal pain, back pain)
- rash, itching
- photosensitivity (a skin reaction on exposure to sunlight) problems with sight tinnitus (ringing in the ears) or hearing loss
- ‘pins-and-needles’ or numbness in your arms, legs, hands or feet problems with blood including its clotting ability and circulation/flow. A decrease in the number of red and white blood cells and platelets in the blood may occur
Disclaimer:
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
